Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 19/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852539 | 0.94 | MAPK1 (0.57) | MAPK1BRD4 | |
| SCHEMBL25970914 | 0.92 | MAPK1 (0.59) | MAPK1 | |
| SCHEMBL25970951 | 0.91 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL25970830 | 0.91 | MAPK1 (0.71) | MAPK1 | |
| SCHEMBL25970926 | 0.90 | MAPK1 (0.60) | MAPK1 | |
| SCHEMBL25971031 | 0.90 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL25856932 | 0.90 | MAPK1 (0.56) | MAPK1 | |
| SCHEMBL25971078 | 0.89 | MAPK1 (0.53) | MAPK1BRD4 | |
| SCHEMBL25853128 | 0.88 | MAPK1 (0.55) | MAPK1BRD4 | |
| SCHEMBL25970906 | 0.88 | MAPK1 (0.53) | MAPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |