Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228098 | 1.00 | TSHR (0.46) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL20846237 | 0.92 | TSHR (0.44) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL22174786 | 0.87 | KMT2A (0.40) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL10280126 | 0.87 | KMT2A (0.40) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL26793785 | 0.87 | KMT2A (0.40) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL772876 | 0.81 | MAPK1 (0.50) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL22455016 | 0.81 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL12449659 | 0.81 | MAPK1 (0.50) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL3010358 | 0.81 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL12369 | 0.81 | MAPK1 (0.50) | TSHRALDH1A1LMNAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |