SCHEMBL25855933

SCHEMBL25855933

c1ccc(C2(c3ccc(-c4cccc5c4Oc4cccc6cccc-5c46)cc3)c3ccccc3-c3ccc4ccccc4c32)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
TYMS P04818 1/20 0.33
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856136 0.93 KDM4E (0.43) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25856301 0.92 KDM4E (0.36) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25855934 0.92 KDM4E (0.38) KDM4EMAPK1ATMMEN1LMNA
SCHEMBL25860398 0.92 KDM4E (0.38) KDM4EMAPK1ATMTYMS
SCHEMBL25855642 0.89 KDM4E (0.45) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25854695 0.87 KDM4E (0.38) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25859796 0.87 KDM4E (0.38) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25844067 0.87 KDM4E (0.40) KDM4EMAPK1ATMTYMS
SCHEMBL25858620 0.87 KDM4E (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25867306 0.87 KDM4E (0.34) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed