SCHEMBL25856140

SCHEMBL25856140

c1ccc(C2(c3ccccc3-c3ccc4c(c3)-c3cccc5cccc(c35)O4)c3ccccc3-c3ccc4ccccc4c32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.44
TYMS P04818 1/20 0.33
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
FYN P06241 1/20 0.30
MAPK3 P27361 1/20 0.30
AHR P35869 1/20 0.30
PAX8 Q06710 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25855937 0.94 KDM4E (0.42) KDM4EMAPK1ATMTYMS
SCHEMBL25856305 0.93 KDM4E (0.41) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25856075 0.93 KDM4E (0.45) KDM4EMAPK1ATMTYMSCYP1A1
SCHEMBL25860060 0.92 KDM4E (0.44) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25844089 0.91 KDM4E (0.46) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25868278 0.90 KDM4E (0.45) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25859892 0.90 MAPK1 (0.51) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25843824 0.89 KDM4E (0.46) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25844074 0.89 KDM4E (0.46) KDM4EMAPK1ATMTYMSMEN1
SCHEMBL25878911 0.89 KDM4E (0.46) KDM4EMAPK1ATMTYMSMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed