Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22642669 | 1.00 | TSHR (0.59) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL25856712 | 1.00 | TSHR (0.59) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL22920282 | 0.93 | TSHR (0.59) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL25058741 | 0.93 | TSHR (0.59) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL24113628 | 0.91 | TSHR (0.57) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL24702509 | 0.91 | TSHR (0.48) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL30481037 | 0.90 | TSHR (0.73) | TSHRFAAHTRPV1ALDH1A1KDM5A | |
| SCHEMBL25961509 | 0.90 | TSHR (0.41) | TSHRFAAHTRPV1 | |
| SCHEMBL25710164 | 0.88 | TSHR (0.70) | TSHRFAAHTRPV1ALDH1A1KDM5A | |
| Hexanal SCHEMBL2635617 | 0.88 | TSHR (0.76) | TSHRFAAHTRPV1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212510-A1 | NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics Inc. (CA) | 2023-07-19 | — | — | EP | disclosed |