Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | POLD1 | P28340 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 17/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21308216 | 0.89 | POLB (0.39) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21307985 | 0.89 | POLB (0.39) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21307979 | 0.88 | POLA1 (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21308175 | 0.88 | POLA1 (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21308020 | 0.88 | POLA1 (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21307990 | 0.88 | POLA1 (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21308225 | 0.88 | POLA1 (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21308150 | 0.85 | POLB (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21307987 | 0.85 | POLB (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21308149 | 0.85 | POLB (0.37) | POLBPOLA1POLD1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227798-A1 | MODIFIED THERMOCCOCUS POLYMERASES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-07-20 | — | — | US | disclosed |