Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852167 | 0.95 | MAPK1 (0.82) | MAPK1 | |
| SCHEMBL21557706 | 0.93 | MAPK1 (0.82) | MAPK1 | |
| SCHEMBL21557701 | 0.93 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL25853245 | 0.93 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL25857130 | 0.93 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL21557657 | 0.92 | MAPK1 (0.81) | MAPK1 | |
| SCHEMBL25852719 | 0.90 | MAPK1 (0.76) | MAPK1 | |
| SCHEMBL20503994 | 0.90 | MAPK1 (0.84) | MAPK1 | |
| SCHEMBL18891669 | 0.90 | MAPK1 (0.78) | MAPK1 | |
| SCHEMBL18860672 | 0.90 | MAPK1 (0.94) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |