Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928087 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL25857292 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL25857295 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL15014467 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL25067256 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL25857294 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL3038968 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL27407439 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL25857291 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 | |
| SCHEMBL5297053 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2KCNH2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | IL17A, IL23R, IL15 | SMN1; SMN2 3490/4885KCNH2 2924/4885CYP2D6 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.