Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694668 | 0.90 | GRM5 (0.46) | GRM5EGLN2APPMRGPRX4BACE1 | |
| SCHEMBL20698865 | 0.86 | GRM5 (0.46) | GRM5EGLN2APPMRGPRX4BACE1 | |
| SCHEMBL4696796 | 0.85 | GRM5 (0.41) | GRM5EGLN2APPMRGPRX4BACE1 | |
| SCHEMBL11741063 | 0.84 | TTR (0.36) | GRM5MRGPRX4GPR35CYP2A6TTR | |
| SCHEMBL20698866 | 0.81 | GRM5 (0.41) | GRM5EGLN2MRGPRX4 | |
| SCHEMBL20681688 | 0.80 | TTR (0.36) | GRM5MRGPRX4GPR35CYP2A6TTR | |
| SCHEMBL25077205 | 0.78 | GRM5 (0.50) | GRM5EGLN2 | |
| SCHEMBL9948037 | 0.78 | GRM5 (0.41) | GRM5EGLN2APPBACE1ALDH1A1 | |
| SCHEMBL4693657 | 0.78 | GRM5 (0.41) | GRM5EGLN2ALDH1A1 | |
| SCHEMBL4651507 | 0.78 | GRM5 (0.41) | GRM5EGLN2APPMRGPRX4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |