SCHEMBL25858740

SCHEMBL25858740

c1ccc(C2(c3ccccc3-c3ccc4c(c3)Oc3ccccc3C43c4ccccc4-c4ccccc43)c3ccccc3-c3ccc4ccccc4c32)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
DHFR P00374 1/20 0.31
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30
KIF11 P52732 1/20 0.30
KDM4E B2RXH2 3/20 0.30
ATM Q13315 2/20 0.30
MAPK1 P28482 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25858737 0.98 KDM4E (0.33) MCL1ACMSDDHFRCHRNA1CHRNG
SCHEMBL25850861 0.94 CHRNA1 (0.31) MCL1ACMSDCHRNA1CHRNGCHRNB1
SCHEMBL25863932 0.94 PDK2 (0.31) DHFRKDM4EMEN1LMNAMAPT
SCHEMBL25864081 0.94 PDK2 (0.31)
SCHEMBL25859031 0.93 PDK2 (0.30) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL25867826 0.93 CHRNA1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL25850637 0.92 PDK2 (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25850394 0.92 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25858514 0.92 KDM4E (0.33) DHFRKDM4EMEN1LMNAMAPT
SCHEMBL25850863 0.92 KDM4E (0.31) KDM4EATMMAPK1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed