SCHEMBL25864328

SCHEMBL25864328

Cc1cccc2c(C3CCC(=O)NC3=O)nn(CC3CC3)c12

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.57
DDB1 Q16531 18/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25027088 0.83 DDB1 (0.77) CRBNDDB1
SCHEMBL29342637 0.74 CRBN (0.73) CRBNDDB1
SCHEMBL25027185 0.73 DDB1 (1.00) CRBNDDB1
SCHEMBL30338206 0.73 DDB1 (1.00) CRBNDDB1
SCHEMBL30257102 0.73 DDB1 (0.75) CRBNDDB1
SCHEMBL25027164 0.73 DDB1 (0.75) CRBNDDB1
SCHEMBL31053795 0.73 DDB1 (0.75) CRBNDDB1
Hydrochloric Acid SCHEMBL31236442 0.72 DDB1 (0.98) CRBNDDB1
SCHEMBL24832984 0.71 DDB1 (0.72) CRBNDDB1
SCHEMBL24132057 0.71 DDB1 (0.72) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131167-A1 COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF 海思科医药集团股份有限公司 2023-07-13 WO disclosed