Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865091 | 0.94 | SCN5A (0.43) | SCN5ASCN9AALDH1A1KDM4EHPGD | |
| SCHEMBL22314953 | 0.89 | SCN5A (0.39) | SCN5AGRIN2BNOTUM | |
| SCHEMBL22314514 | 0.89 | SCN5A (0.45) | SCN5AGRIN2BNOTUMPSD | |
| SCHEMBL25865032 | 0.88 | SCN5A (0.44) | SCN5AGRIN2BNOTUMPSD | |
| SCHEMBL22314952 | 0.86 | SCN5A (0.38) | SCN5AALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL22314548 | 0.85 | SCN5A (0.43) | SCN5AALDH1A1KDM4EGRIN2BDYRK1A | |
| SCHEMBL22314910 | 0.85 | SCN5A (0.40) | SCN5ASCN9AGRIN2BNOTUMBRD4 | |
| SCHEMBL22314905 | 0.85 | SCN5A (0.40) | SCN5ASCN9AGRIN2BNOTUMBRD4 | |
| SCHEMBL22315052 | 0.85 | SCN5A (0.40) | SCN5ASCN9AGRIN2BNOTUMBRD4 | |
| SCHEMBL20472119 | 0.85 | SCN5A (0.40) | SCN5AGRIN2BPSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | SCN5A 8/4885SCN9A 42/4885ALDH1A1 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.