Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | CDC7 | O00311 | 7/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.39 |
| ▸ | PRKACA | P17612 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865837 | 0.89 | HTR2A (0.65) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL30509693 | 0.83 | HTR2A (0.68) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL25865698 | 0.83 | HTR2A (0.68) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL25865890 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL25429922 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL30532644 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL30532650 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL26646622 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL30509688 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 | |
| SCHEMBL26646654 | 0.77 | HTR2A (1.00) | HTR2AHTR2CHTR2BCDC7MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |