Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 5/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865804 | 0.86 | HTR2A (0.47) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| Hydrochloric Acid SCHEMBL31327403 | 0.85 | HTR2A (0.46) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| SCHEMBL25865989 | 0.85 | HTR2A (0.46) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| Hydrochloric Acid SCHEMBL25429456 | 0.84 | HTR2A (0.46) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| Hydrochloric Acid SCHEMBL30509701 | 0.84 | HTR2A (0.46) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| SCHEMBL25867212 | 0.83 | HTR2A (0.45) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| Hydrochloric Acid SCHEMBL25427976 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| Hydrochloric Acid SCHEMBL30509708 | 0.82 | HTR2A (0.44) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| SCHEMBL25865817 | 0.79 | HTR2A (0.47) | HTR2AHTR2CHTR2BCDK2CCNT1 | |
| SCHEMBL12422660 | 0.78 | TMEM97 (0.53) | HTR2AHTR2CHTR2BCDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |