SCHEMBL2586658

SCHEMBL2586658

NCC(=O)OC(=O)OC(=O)CN.[LiH].[LiH]

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.37
SLC6A9 P48067 1/20 0.37
OR51E2 Q9H255 1/20 0.37
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723808 0.97 GLRA1 (0.39) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL583140 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL16602 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL6237274 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL1666322 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL25362121 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL6237184 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL28221695 0.94 GLRA1 (0.37) GLRA1SLC6A9OR51E2KDM4ELMNA
Hydrochloric Acid SCHEMBL22518913 0.88 KDM4E (0.34) GLRA1SLC6A9OR51E2KDM4ELMNA
SCHEMBL28013370 0.86 GLRA1 (0.32) GLRA1SLC6A9OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110268235-A1 BORON-10 ENHANCED THERMAL ENERGY GURIN MICHAEL 2011-11-03 US claimed
WO-2005011737-A2 PHARMACEUTICAL COMBINATIONS AND FORMULATIONS WITH IMPROVED STABILITY CIPLA LIMITED (IN) 2005-02-10 WO claimed
EP-1006997-B1 EFFERVESCENT MICROSPHERES AND METHOD FOR MAKING THEM PF MEDICAMENT (FR) 2003-07-02 EP claimed
US-6210711-B1 MULTILAYER MICROSPHERES CONTAINING AN ACID SUBSTANCE, A BASIC SUBSTANCE, AND A WATER-SOLUBLE ISOLATING AGENT WHICH, WHEN IT DISSOLVES IN WATER, AFTER ALMOST INSTANT EFFERVESCENCE, BRINGS ABOUT A HOMOGENEOUS DISPERSION OF ACTIVE PRINCIPAL(S) PIERRE FABRE MEDICAMENT (FR) 2001-04-03 US claimed
US-9951949-B1 Ultra-high energy density and emissivity for energy conversion GURIN MICHAEL H (US) 2018-04-24 US disclosed
US-20110268235-A1 BORON-10 ENHANCED THERMAL ENERGY GURIN MICHAEL 2011-11-03 US disclosed
US-20070218131-A1 EFFERVESCENT FORMULATIONS COMPRISING DESMOPRESSIN ARDANA BIOSCIENCE LIMITED (GB) 2007-09-20 US disclosed
CN-1953738-A Effervescent agent containing desmopressin ARDANA BIOSCIENCE LTD (GB) 2007-04-25 CN disclosed
US-20070087054-A1 EFFERVESCENT FORMULATIONS OF OXYTOCIN ARDANA BIOSCIENCE LIMITED (GB) 2007-04-19 US disclosed
US-20070071818-A1 EFFERVESCENT FORMULATIONS COMPRISING APOMORPHINE ARDANA BIOSCIENCE LIMITED (GB) 2007-03-29 US disclosed
EP-1725220-A1 EFFERVESCENT FORMULATIONS COMPRISING DESMOPRESSIN Ardana Bioscience Limited (GB) 2006-11-29 EP disclosed
US-20060141032-A1 Effervescent formulations comprising apomorphine ARDANA BIOSCIENCE LIMITED (GB) 2006-06-29 US disclosed
US-20060034920-A1 Effervescent formulations of oxytocin ARDANA BIOSCIENCE LIMITED (GB) 2006-02-16 US disclosed
WO-2005089724-A1 EFFERVESCENT FORMULATIONS COMPRISING DESMOPRESSIN ARDANA BIOSCIENCE LIMITED (GB) 2005-09-29 WO disclosed
EP-1556048-A1 EFFERVESCENT FORMULATIONS COMPRISING APOMORPHINE Ardana Bioscience Limited (GB) 2005-07-27 EP disclosed
EP-1549289-A1 EFFERVESCENT FORMULATIONS OF OXYTOCIN Ardana Bioscience Limited (GB) 2005-07-06 EP disclosed
WO-2005011737-A2 PHARMACEUTICAL COMBINATIONS AND FORMULATIONS WITH IMPROVED STABILITY CIPLA LIMITED (IN) 2005-02-10 WO disclosed
WO-2004026279-A1 EFFERVESCENT FORMULATIONS OF OXYTOCIN ARDANA BIOSCIENCE LIMITED (GB) 2004-04-01 WO disclosed
WO-2004026309-A1 EFFERVESCENT FORMULATIONS COMPRISING APOMORPHINE ARDANA BIOSCIENCE LIMITED (GB) 2004-04-01 WO disclosed
US-6210711-B1 MULTILAYER MICROSPHERES CONTAINING AN ACID SUBSTANCE, A BASIC SUBSTANCE, AND A WATER-SOLUBLE ISOLATING AGENT WHICH, WHEN IT DISSOLVES IN WATER, AFTER ALMOST INSTANT EFFERVESCENCE, BRINGS ABOUT A HOMOGENEOUS DISPERSION OF ACTIVE PRINCIPAL(S) PIERRE FABRE MEDICAMENT (FR) 2001-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218131-A1 EFFERVESCENT FORMULATIONS COMPRISING DESMOPRESSIN AVPR2, AVPR1A, AVPR1B GLRA1 1689/4885SLC6A9 924/4885OR51E2 1120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.