Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040995 | 0.87 | USP2 (0.55) | USP2SMN1; SMN2RECQLSCD5CYP11B2 | |
| SCHEMBL31068229 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2RECQLSCD5CYP11B2 | |
| SCHEMBL25278015 | 0.85 | USP2 (0.51) | USP2SMN1; SMN2RECQLSCD5CYP11B2 | |
| SCHEMBL31299280 | 0.83 | USP2 (0.61) | USP2SMN1; SMN2RECQLHPGDEPHX2 | |
| SCHEMBL31299440 | 0.83 | USP2 (0.61) | USP2SMN1; SMN2RECQLHPGDEPHX2 | |
| SCHEMBL16903431 | 0.83 | USP2 (0.61) | USP2SMN1; SMN2RECQLHPGDEPHX2 | |
| SCHEMBL15649307 | 0.83 | USP2 (0.61) | USP2SMN1; SMN2RECQLSCD5HDAC2 | |
| SCHEMBL13452494 | 0.83 | SMN1; SMN2 (0.61) | USP2SMN1; SMN2RECQLSCD5CYP11B2 | |
| SCHEMBL15817589 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2RECQLSCD5CYP11B2 | |
| SCHEMBL15119428 | 0.83 | USP2 (0.51) | USP2SMN1; SMN2RECQLSCD5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |