SCHEMBL2586706

SCHEMBL2586706

Cc1nc[nH]c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677524 0.71
SCHEMBL17773604 0.70
Bromide SCHEMBL7030389 0.69
SCHEMBL12244444 0.69 HPGD (0.36)
SCHEMBL22125883 0.67
SCHEMBL1566892 0.67
SCHEMBL20683223 0.67
SCHEMBL20844021 0.67
SCHEMBL5634287 0.67
SCHEMBL21212846 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117111404-A Extreme ultraviolet photoresist and preparation method thereof 中国科学院上海微系统与信息技术研究所 2023-11-24 CN claimed
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 EP disclosed
US-20250289799-A1 PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL USE THEREOF JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2025-09-18 US disclosed
EP-4045493-B1 COMPOUNDS FOR TARGETED DEGRADATION OF CARRIER PROTEINS AND USES THEREOF CEMM FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH (AT) 2025-08-13 EP disclosed
EP-4585596-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF Shanghai Yingli Pharmaceutical Co., Ltd (CN) 2025-07-16 EP disclosed
US-20250195480-A1 MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS Fulcrum Therapeutics, Inc. 2025-06-19 US disclosed
EP-4537902-A2 TRICYCLIC ASK1 INHIBITORS Terns, Inc. (US) 2025-04-16 EP disclosed
EP-4516779-A1 PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-03-05 EP disclosed
WO-2025007777-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2025-01-09 WO disclosed
EP-3773577-B1 TRICYCLIC ASK1 INHIBITORS TERNS INC (US) 2024-11-20 EP disclosed
US-20110275631-A1 Heteroaryl Substituted Indole Compounds Useful as MMP-13 Inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-11-10 US disclosed
US-20110275631-A1 Heteroaryl Substituted Indole Compounds Useful as MMP-13 Inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-11-10 US disclosed
WO-2010045188-A1 HETEROARYL SUBSTITUTED INDOLE COMPOUNDS USEFUL AS MMP-13 INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-22 WO disclosed
CN-1109021-C Method of producing N, N'-diazole compounds PPG INDUSTRIES INC (US) 2003-05-21 CN disclosed
EP-1019381-A1 METHOD OF PRODUCING N,N'-DIAZOLE COMPOUNDS PPG INDUSTRIES, INC. (US) 2000-07-19 EP disclosed
CN-1248247-A Preparation method of N, N' -diazole compound PPG INDUSTRIES INC (US) 2000-03-22 CN disclosed
WO-1998031672-A1 METHOD OF PRODUCING N,N'-DIAZOLE COMPOUNDS PPG INDUSTRIES OHIO, INC. (US) 1998-07-23 WO disclosed
EP-0139135-B1 4-ALKYLIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION BASF Aktiengesellschaft (DE) 1987-07-08 EP disclosed
US-4602927-A 4-alkylimidazole derivatives and their use as nitrification inhibitors BASF AKTIENGESELLSCHAFT (DE) 1986-07-29 US disclosed
EP-0139135-A1 4-Alkylimidazole derivatives, their preparation and their application BASF Aktiengesellschaft (DE) 1985-05-02 EP disclosed