Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 19/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259477 | 0.87 | PIK3C3 (0.58) | PIK3C3PIK3CAPIK3CBPIK3CG | |
| SCHEMBL20765439 | 0.87 | PIK3C3 (0.62) | PIK3C3PDCD1CD274 | |
| SCHEMBL19276422 | 0.87 | PIK3C3 (0.53) | PIK3C3PIK3CAPIK3CBPIK3CG | |
| SCHEMBL19259449 | 0.87 | PIK3C3 (0.53) | PIK3C3PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24224332 | 0.85 | PIK3C3 (0.45) | PIK3C3PDCD1CD274 | |
| SCHEMBL20765445 | 0.85 | PIK3C3 (0.51) | PIK3C3PDCD1CD274 | |
| SCHEMBL20765566 | 0.85 | PIK3C3 (0.53) | PIK3C3PDCD1CD274 | |
| SCHEMBL20777081 | 0.85 | PIK3C3 (0.51) | PIK3C3PDCD1CD274 | |
| SCHEMBL20765501 | 0.85 | PIK3C3 (0.53) | PIK3C3PIK3CAPIK3CBPIK3CG | |
| SCHEMBL20765346 | 0.84 | PIK3C3 (0.51) | PIK3C3PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234949-A1 | MORPHOLINYLPYRIDONE COMPOUNDS | SPRINT BIOSCIENCE AB (SE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234949-A1 | MORPHOLINYLPYRIDONE COMPOUNDS | MAP1B, RRP12, MYT1 | PIK3C3 3821/4885PIK3CA 3744/4885PIK3CB 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.