Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 12/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698324 | 1.00 | ASGR1 (0.64) | ASGR1HPSESMN1; SMN2 | |
| SCHEMBL26888865 | 1.00 | ASGR1 (0.64) | ASGR1HPSESMN1; SMN2 | |
| SCHEMBL26877378 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL25867158 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL26877366 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL26698319 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL17268879 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL25874663 | 0.82 | ASGR1 (0.63) | ASGR1 | |
| SCHEMBL25867164 | 0.81 | ASGR1 (0.52) | ASGR1 | |
| SCHEMBL25867165 | 0.81 | ASGR1 (0.64) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | ASGR1 1/4885HPSE 362/4885SMN1; SMN2 3100/4885 |
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR2A | ASGR1 1/4885HPSE 412/4885SMN1; SMN2 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.