Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848840 | 0.96 | HSD17B10 (0.45) | PDE8BATMHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL5849346 | 0.96 | HSD17B10 (0.45) | PDE8BATMHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL5851050 | 0.96 | HSD17B10 (0.45) | PDE8BATMHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL15481738 | 0.90 | HSD17B10 (0.38) | PDE8BATMHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL4400837 | 0.87 | PDE8B (0.47) | PDE8BKDM1AATMHSD17B10HPGD | |
| SCHEMBL11990570 | 0.87 | PDE8B (0.47) | PDE8BKDM1AATMHSD17B10HPGD | |
| SCHEMBL11995153 | 0.87 | PDE8B (0.47) | PDE8BKDM1AATMHSD17B10HPGD | |
| SCHEMBL7203146 | 0.84 | PDE8B (0.46) | PDE8BKDM1AATMHSD17B10HPGD | |
| SCHEMBL6536205 | 0.84 | PDE8B (0.46) | PDE8BKDM1AATMHSD17B10HPGD | |
| SCHEMBL771460 | 0.84 | PDE8B (0.47) | PDE8BKDM1AATMHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355299-A | Substituted 2- (2, 6-dioxopiperidin-3-yl) -5- (1-piperidin-4-yl) isoindoline-1, 3-dione derivatives and uses thereof | 尼奥莫夫公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116615199-A | Heterocyclic compounds as diacylglycerol kinase inhibitors and uses thereof | 株式会社LG化学 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023133336-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| CN-104507936-A | Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives | FORMA TM LLC | 2015-04-08 | — | — | CN | disclosed |