⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152748 | 0.82 | — | — | |
| SCHEMBL28079201 | 0.76 | — | — | |
| SCHEMBL48851 | 0.73 | — | — | |
| SCHEMBL28852577 | 0.71 | — | — | |
| SCHEMBL18445851 | 0.71 | — | — | |
| Fluoride SCHEMBL27856600 | 0.71 | KDM4E (0.48) | — | |
| SCHEMBL4529479 | 0.71 | — | — | |
| SCHEMBL3740454 | 0.71 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL21872285 | 0.71 | SMN1; SMN2 (0.53) | — | |
| Hydrochloric Acid SCHEMBL1485396 | 0.70 | SMN1; SMN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227499-A1 | PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2023-07-20 | — | — | US | disclosed |
| CN-106061963-B | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-109789132-A | For treating double leucine zippers (DLK) kinase inhibitor of disease | 德州大学系统董事会 | 2019-05-21 | — | — | CN | disclosed |
| CN-101568542-B | 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-101568542-A | 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-28 | — | — | CN | disclosed |