Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1880398 | 0.85 | USP2 (0.51) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL3494732 | 0.84 | USP2 (0.43) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL22188561 | 0.83 | USP2 (0.42) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL12884306 | 0.81 | USP2 (0.47) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL6750190 | 0.80 | USP2 (0.39) | USP2SMN1; SMN2NR1H2HPGDEPHX2 | |
| SCHEMBL6750199 | 0.80 | USP2 (0.39) | USP2SMN1; SMN2NR1H2HPGDEPHX2 | |
| SCHEMBL23070921 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL3164042 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| Bicarbonate SCHEMBL31475110 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL3158101 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2NR1H2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639357-B2 | Dihydrochromene derivatives | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639357-B2 | Dihydrochromene derivatives | H1-3, H1-2, H1-0 | USP2 3979/4885SMN1; SMN2 3519/4885NR1H2 612/4885 |
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | H1-3, H1-2, H1-0 | USP2 3979/4885SMN1; SMN2 3519/4885NR1H2 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.