Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRPR | P30550 | 3/20 | 0.56 |
| ▸ | GLP1R | P43220 | 12/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31211798 | 0.91 | ERAP2 (0.57) | GRPRGLP1RGCGR | |
| SCHEMBL25897599 | 0.91 | GLP1R (0.54) | GRPRGLP1RKEAP1GCGR | |
| SCHEMBL26187823 | 0.91 | GLP1R (0.53) | GRPRGLP1RKEAP1GCGR | |
| SCHEMBL23346183 | 0.89 | GLP1R (0.53) | GLP1RKEAP1GCGR | |
| SCHEMBL24918846 | 0.88 | GRPR (0.55) | GRPRGLP1RKEAP1GCGR | |
| SCHEMBL31211817 | 0.87 | GRPR (0.55) | GRPRGLP1R | |
| SCHEMBL20694362 | 0.87 | GRPR (0.56) | GRPRGLP1RKEAP1GCGR | |
| SCHEMBL31053727 | 0.87 | ERAP2 (0.57) | GRPRGLP1RNPBWR1 | |
| SCHEMBL31688317 | 0.86 | GRPR (0.59) | GRPRGLP1R | |
| SCHEMBL24918843 | 0.85 | GRPR (0.54) | GRPRGLP1RKEAP1NPBWR1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR2A | GRPR 1425/4885GLP1R 2831/4885KEAP1 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.