Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 20/20 | 0.57 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17293012 | 0.89 | MALT1 (0.55) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293010 | 0.89 | MALT1 (0.55) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL18787821 | 0.89 | MALT1 (0.55) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293032 | 0.88 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293034 | 0.88 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL18862728 | 0.83 | MALT1 (0.46) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL19826562 | 0.80 | MALT1 (0.44) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL30606704 | 0.80 | MALT1 (0.68) | MALT1BIRC3 | |
| SCHEMBL30606679 | 0.80 | MALT1 (0.68) | MALT1BIRC3 | |
| SCHEMBL30595723 | 0.78 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139479-A1 | SUBSTITUTED BICYCLIC HETEROCYCLES AS MALT-1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-07-27 | — | — | WO | disclosed |