Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 17/20 | 0.40 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870148 | 0.82 | MALT1 (0.38) | MALT1BIRC3 | |
| SCHEMBL17292962 | 0.75 | MALT1 (0.40) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17292964 | 0.75 | MALT1 (0.40) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL18839705 | 0.70 | MALT1 (0.41) | MALT1BIRC3 | |
| SCHEMBL18839476 | 0.68 | MALT1 (0.65) | MALT1BIRC3 | |
| SCHEMBL18839583 | 0.68 | MALT1 (0.64) | MALT1BIRC3 | |
| SCHEMBL18839867 | 0.68 | MALT1 (0.83) | MALT1BIRC3 | |
| SCHEMBL17293093 | 0.67 | CYP1A2 (0.51) | MALT1BIRC3 | |
| SCHEMBL17293094 | 0.67 | CYP1A2 (0.51) | MALT1BIRC3 | |
| SCHEMBL31259307 | 0.67 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139479-A1 | SUBSTITUTED BICYCLIC HETEROCYCLES AS MALT-1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-07-27 | — | — | WO | disclosed |