Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17944007 | 0.82 | CYP1A1 (0.40) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL17944997 | 0.82 | CYP1A1 (0.40) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL24341584 | 0.81 | CYP1A1 (0.39) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL17944555 | 0.81 | CYP1A1 (0.39) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL24341854 | 0.81 | NPC1 (0.39) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL17945113 | 0.81 | CYP1A1 (0.39) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL25873156 | 0.81 | MAPT (0.46) | CYP1A1CYP1B1NPC1RAB9ATDP1 | |
| SCHEMBL19109838 | 0.80 | NPC1 (0.38) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL24340999 | 0.80 | CYP1A1 (0.39) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 | |
| SCHEMBL23502248 | 0.80 | CYP1A1 (0.40) | CYP1A1CYP1B1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | INF2, INTS9, PYM1 | CYP1A1 1285/4885CYP1B1 1019/4885NPC1 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.