Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.39 |
| ▸ | MTOR | P42345 | 17/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876241 | 0.89 | MEN1 (0.31) | — | |
| SCHEMBL25875947 | 0.89 | MEN1 (0.37) | PIK3CAMTOR | |
| SCHEMBL25875975 | 0.88 | — | — | |
| SCHEMBL25876281 | 0.87 | PDE1A (0.34) | — | |
| SCHEMBL25876085 | 0.86 | MERTK (0.33) | — | |
| SCHEMBL25875751 | 0.84 | TP53 (0.32) | PIK3CAPDE2A | |
| SCHEMBL25875899 | 0.83 | KLKB1 (0.33) | — | |
| SCHEMBL25884292 | 0.83 | PIK3CA (0.35) | PIK3CAMTORPDE2APIK3CD | |
| SCHEMBL25876137 | 0.81 | PIK3CA (0.35) | PIK3CAMTOR | |
| SCHEMBL25876054 | 0.80 | PDE9A (0.31) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234954-A1 | COMPOUND USED AS RET KINASE INHIBITOR AND APPLICATION THEREOF | TYK MEDICINES, INC. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234954-A1 | COMPOUND USED AS RET KINASE INHIBITOR AND APPLICATION THEREOF | RET, ROR1, FGFR3 | PIK3CA 487/4885MTOR 390/4885PDE2A 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.