SCHEMBL2587725

SCHEMBL2587725

CC1(C)C(=CC=C2CCCC(C=CC3=[N+](CCO)c4ccccc4C3(C)C)=C2Cl)N(CCO)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.48
APP P05067 1/20 0.47
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
USP2 O75604 1/20 0.45
S1PR2 O95136 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
ALPG P10696 1/20 0.45
THRB P10828 1/20 0.45
PKM P14618 1/20 0.45
XBP1 P17861 1/20 0.45
CRHBP P24387 1/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
RAB9A P51151 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
CRHR2 Q13324 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066306 1.00 PRMT1 (0.48) PRMT1APPMEN1NPC1USP2
Perchlorate SCHEMBL343336 0.98 MEN1 (0.49) PRMT1APPMEN1NPC1USP2
SCHEMBL7604098 0.96 PRMT1 (0.49) PRMT1APPMEN1NPC1USP2
SCHEMBL12020885 0.92 PRMT1 (0.53) PRMT1APPMEN1NPC1USP2
SCHEMBL12713687 0.91 PRMT1 (0.52) PRMT1APPMEN1NPC1USP2
SCHEMBL22987365 0.91 PRMT1 (0.51) PRMT1APPMEN1NPC1USP2
SCHEMBL14671412 0.91 PRMT1 (0.51) PRMT1APPMEN1NPC1USP2
SCHEMBL15026324 0.89 PRMT1 (0.49) PRMT1APPMEN1NPC1USP2
SCHEMBL12355233 0.89 PRMT1 (0.49) PRMT1APPMEN1NPC1USP2
SCHEMBL1925058 0.89 PRMT1 (0.49) PRMT1APPMEN1NPC1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8050745-B2 Methods and systems for enhanced medical procedure visualization DOHENY EYE INSTITUTE (US) 2011-11-01 US disclosed
US-20070244367-A1 Methods and systems for enhanced medical procedure visualization DOHENY EYE INSTITUTE (US) 2007-10-18 US disclosed