Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484596 | 0.92 | BACE1 (0.68) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25312572 | 0.92 | BACE1 (0.68) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25881360 | 0.89 | BACE1 (0.58) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25885546 | 0.89 | LANCL2 (0.54) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25312635 | 0.86 | BACE1 (0.54) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25878635 | 0.85 | LANCL2 (0.54) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25312109 | 0.84 | KDM4E (0.56) | BACE1BACE2CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL25311124 | 0.84 | LANCL2 (0.59) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL29466265 | 0.84 | LANCL2 (0.59) | LANCL2BACE1BACE2CYP3A4HDAC1 | |
| SCHEMBL25879262 | 0.83 | BACE1 (0.54) | LANCL2BACE1BACE2CYP3A4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |