SCHEMBL25879163

SCHEMBL25879163

c1ccc2c(c1)Oc1ccc(-c3ccc4c(c3)C3(c5ccccc5-4)c4c(ccc5ccccc45)-c4ccc5ccccc5c43)c3cccc-2c13

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MCL1 Q07820 1/20 0.30
ACMSD Q8TDX5 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25843930 0.98 KDM4E (0.43) MAPK1KDM4EATMMCL1ACMSD
SCHEMBL25869858 0.95 KDM4E (0.40) MAPK1KDM4EATM
SCHEMBL25868557 0.94 MAPK1 (0.41) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL25868935 0.94 KDM4E (0.41) MAPK1KDM4EATMENPP3ENPP1
SCHEMBL25843815 0.92 KDM4E (0.42) MAPK1KDM4EATMMCL1ACMSD
SCHEMBL25841650 0.90 KDM4E (0.43) MAPK1KDM4EATM
SCHEMBL25903818 0.90 KDM4E (0.43) MAPK1KDM4EATM
SCHEMBL25879100 0.89 KDM4E (0.41) MAPK1KDM4EATM
SCHEMBL25843362 0.89 MAPK1 (0.48) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL25859505 0.88 KDM4E (0.42) MAPK1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed