Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 7/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471177 | 1.00 | LANCL2 (0.65) | LANCL2PARP1NAMPTCKS1BSKP1 | |
| SCHEMBL25879553 | 0.86 | LANCL2 (0.60) | LANCL2PARP1BCHESMN1; SMN2 | |
| SCHEMBL25878837 | 0.86 | LANCL2 (0.74) | LANCL2JAK1HSD11B1SMN1; SMN2 | |
| SCHEMBL25312485 | 0.86 | LANCL2 (0.74) | LANCL2JAK1HSD11B1SMN1; SMN2 | |
| SCHEMBL29484628 | 0.85 | CKS1B (0.52) | LANCL2PARP1CKS1BSKP1SKP2 | |
| SCHEMBL25879958 | 0.85 | LANCL2 (0.76) | LANCL2JAK1HSD11B1SMN1; SMN2 | |
| SCHEMBL17706597 | 0.84 | LANCL2 (0.78) | LANCL2PARP1NAMPTCKS1BSKP1 | |
| SCHEMBL29063415 | 0.81 | LANCL2 (0.84) | LANCL2HSD11B1SMN1; SMN2 | |
| SCHEMBL25879427 | 0.81 | LANCL2 (0.69) | LANCL2PARP1 | |
| SCHEMBL25878863 | 0.81 | LANCL2 (0.68) | LANCL2PARP1JAK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |