SCHEMBL25879554

SCHEMBL25879554

NC(=O)c1cccc(-c2nc3ccccc3[nH]2)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LANCL2 Q9NS86 1/20 0.71
RAB9A P51151 8/20 0.53
NPC1 O15118 7/20 0.53
SMN1; SMN2 Q16637 6/20 0.53
KDM4E B2RXH2 6/20 0.53
HPGD P15428 4/20 0.53
ALDH1A1 P00352 4/20 0.53
TP53 P04637 4/20 0.53
PKM P14618 3/20 0.53
HSD17B10 Q99714 2/20 0.53
ALOX15 P16050 2/20 0.53
TSHR P16473 2/20 0.53
METAP2 P50579 2/20 0.53
METAP1 P53582 2/20 0.53
LMNA P02545 1/20 0.53
MTOR P42345 1/20 0.53
ABCB11 O95342 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
FKBP1A P62942 2/20 0.49
ADORA3 P0DMS8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466292 0.88 LANCL2 (0.71) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL17700974 0.87 LANCL2 (0.69) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL29466277 0.87 LANCL2 (0.69) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL29484573 0.85 LANCL2 (0.67) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
Omilancor SCHEMBL29349469 0.83 LANCL2 (1.00) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
Omilancor SCHEMBL17706588 0.83 LANCL2 (1.00) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL3121939 0.82 LANCL2 (0.63) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL17705597 0.81 LANCL2 (0.62) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL30471353 0.81 LANCL2 (0.62) LANCL2RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL18426899 0.81 LANCL2 (0.62) LANCL2RAB9ANPC1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4215526-A1 CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF Shanghai Pharmaceuticals Holding Co., Ltd. (CN) 2023-07-26 EP disclosed
CN-101376663-B 6-benzimidazole-pyridine-2- formiate amide metal complexe, preparation and use CHINA PETROCHEMICAL CO LTD 2011-06-15 CN disclosed
CN-101376663-B 6-benzimidazole-pyridine-2- formiate amide metal complexe, preparation and use CHINA PETROCHEMICAL CO LTD 2011-06-15 CN disclosed
CN-101575387-A Olefin polymerization catalyst and preparation method and application thereof PETROCHINA CO LTD (CN) 2009-11-11 CN disclosed
CN-101376663-A 6-benzimidazole-pyridine-2- formiate amide metal complexe, preparation and use CHINA PETROCHEMICAL CO LTD (CN) 2009-03-04 CN disclosed
CN-101376663-A 6-benzimidazole-pyridine-2- formiate amide metal complexe, preparation and use CHINA PETROCHEMICAL CO LTD (CN) 2009-03-04 CN disclosed