Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484599 | 1.00 | KDM4E (0.47) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25311896 | 1.00 | KDM4E (0.47) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25878406 | 1.00 | KDM4E (0.47) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25878144 | 0.86 | KDM4E (0.57) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25883229 | 0.80 | KDM4E (0.58) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25883242 | 0.78 | KDM4E (0.59) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25883304 | 0.78 | KDM4E (0.59) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25311688 | 0.77 | KDM4E (0.54) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL25315909 | 0.77 | KDM4E (0.47) | KDM4ESMN1; SMN2RAB9ALMNAPOLB | |
| SCHEMBL27180290 | 0.77 | KDM4E (0.47) | KDM4ESMN1; SMN2RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |