⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23324922 | 0.86 | — | — | |
| SCHEMBL25953110 | 0.83 | HRH3 (0.30) | — | |
| SCHEMBL18505952 | 0.73 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL12205479 | 0.71 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL23323492 | 0.70 | USP30 (0.31) | — | |
| SCHEMBL23324541 | 0.69 | — | — | |
| SCHEMBL19504943 | 0.69 | — | — | |
| SCHEMBL25905688 | 0.69 | CYP2D6 (0.33) | — | |
| SCHEMBL25953112 | 0.68 | — | — | |
| SCHEMBL25953199 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234929-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |