Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.41 |
| ▸ | TNF | P01375 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897832 | 0.90 | TIPARP (0.49) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL25898542 | 0.89 | TIPARP (0.48) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL25898391 | 0.88 | TIPARP (0.46) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL26787804 | 0.88 | TIPARP (0.44) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL26793446 | 0.87 | TIPARP (0.49) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL25899141 | 0.85 | TIPARP (0.47) | TIPARPTNF | |
| SCHEMBL25898159 | 0.83 | TIPARP (0.43) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL25899282 | 0.83 | TIPARP (0.43) | TIPARPGRM2TNFHDAC3HDAC1 | |
| SCHEMBL25900117 | 0.83 | TIPARP (0.46) | TIPARPGRM2TNFLMNASMN1; SMN2 | |
| SCHEMBL25899897 | 0.82 | TIPARP (0.51) | TIPARPGRM2TNFHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |