Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 12/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.55 |
| ▸ | DNMT3B | Q9UBC3 | 6/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.49 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | INMT | O95050 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | HNMT | P50135 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.49 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21553887 | 0.81 | DOT1L (0.55) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL21553884 | 0.76 | DOT1L (0.59) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL25899380 | 0.74 | DOT1L (0.57) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL18137735 | 0.73 | DOT1L (0.53) | DOT1LEZH2 | |
| SCHEMBL21553970 | 0.73 | DOT1L (0.58) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL14191440 | 0.72 | DOT1L (1.00) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL14174642 | 0.72 | DOT1L (1.00) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL9058595 | 0.72 | DOT1L (1.00) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL14174641 | 0.71 | DOT1L (1.00) | DOT1LPRMT1DNMT3BEZH2DNMT1 | |
| SCHEMBL30979358 | 0.71 | DOT1L (0.85) | DOT1LPRMT1DNMT3BEZH2DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219518-A2 | BIOCONJUGATES OF HETEROCYCLIC COMPOUNDS | Taizhou Huifeng Hetai Biotechnology Co. Ltd (CN) | 2023-08-02 | — | — | EP | disclosed |