Sugi Predict

Sugi Predict / Compounds / SCHEMBL2590108

SCHEMBL2590108

SCHEMBL2590108

c1cnc(-n2ccc3ccccc32)nc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RPS6KA5 O75582 3/20 0.60
▸ CDC7 O00311 1/20 0.54
▸ CDK2 P24941 1/20 0.54
▸ ROCK1 Q13464 1/20 0.54
▸ BIRC5 O15392 1/20 0.48
▸ RPS6KA4 O75676 1/20 0.47
▸ PRKD3 O94806 1/20 0.47
▸ PRKCG P05129 1/20 0.47
▸ PRKCB P05771 1/20 0.47
▸ PRKCA P17252 1/20 0.47
▸ PRKACA P17612 1/20 0.47
▸ PRKACG P22612 1/20 0.47
▸ PRKACB P22694 1/20 0.47
▸ PRKCH P24723 1/20 0.47
▸ PRKCI P41743 1/20 0.47
▸ PRKCE Q02156 1/20 0.47
▸ PRKCQ Q04759 1/20 0.47
▸ PRKCZ Q05513 1/20 0.47
▸ PRKCD Q05655 1/20 0.47
▸ PRKD1 Q15139 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388240 1.00 RPS6KA5 (0.60) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL13052919 0.85 BIRC5 (0.59) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL28389224 0.84 CDC7 (0.47) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL18803631 0.82 MKNK1 (0.60) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL29975548 0.81 CDC7 (0.45) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL524138 0.80 CDC7 (0.60) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL29388549 0.80 CDC7 (0.60) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL31107087 0.80 CDC7 (0.60) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL7867877 0.78 CDC7 (0.47) RPS6KA5CDC7CDK2ROCK1BIRC5
SCHEMBL23559754 0.77 CDC7 (0.42) RPS6KA5CDC7CDK2ROCK1BIRC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116288422-A Method for realizing 2-position alkylation of indole by utilizing micro-channel photoelectrocatalysis technology and product 南京工业大学 2023-06-23 — — CN claimed
CN-109678810-B 1,2-oxygen nitrogen heterocyclic butane compound and preparation method and application thereof 南京工业大学 2022-10-28 — — CN claimed
CN-110563701-B N-2-pyrimidine-2-azido-3- (2,2,6, 6-tetramethylpiperidinyloxy) indoline and preparation and application thereof 浙江工业大学 2022-09-16 — — CN claimed
CN-112574180-B N-2-pyrimidinyl-3-fluoroindole compound and preparation method and application thereof 浙江工业大学 2021-10-15 — — CN claimed
CN-111039927-B Method for synthesizing beta-aryl ketone at room temperature by using reusable catalytic system 陕西科技大学 2021-04-13 — — CN claimed
CN-112574180-A N-2-pyrimidinyl-3-fluoroindole compound and preparation method and application thereof 浙江工业大学 2021-03-30 — — CN claimed
US-10940468-B2 Nickel catalyst, process for preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-03-09 — — US claimed
CN-111039927-A Method for synthesizing β -aryl ketone at room temperature by using reusable catalytic system 陕西科技大学 2020-04-21 — — CN claimed
CN-106279236-B Method for synthesizing 2-triisopropyl silicon-based acetylene indole compound 南京理工大学 2020-04-10 — — CN claimed
CN-110563701-A N-2-pyrimidine-2-azido-3- (2,2,6, 6-tetramethylpiperidinyloxy) indoline and preparation and application thereof 浙江工业大学 2019-12-13 — — CN claimed
WO-2017154022-A1 NOVEL NICKEL CATALYST, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-09-14 — — WO claimed
CN-101257948-A Pyrimidine-fused diazepine derivatives and indole-fused pteridines ATTENUON LLC (US) 2008-09-03 — — CN claimed
US-20260015332-A1 SYNTHESIS METHOD AND APPLICATION OF BENZOTHIASELENAZOLE-1-OXIDE COMPOUND AND DERIVATIVE THEREOF GUANGZHOU MEDICAL UNIVERSITY (CN) 2026-01-15 — — US disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 — — US disclosed
WO-2023169082-A1 SYNTHESIS METHOD AND APPLICATION OF BENZOTHIADIAZOLE-1-KETONE COMPOUND AND DERIVATIVE THEREOF 广州医科大学 2023-09-14 — — WO disclosed
CN-116514781-A Fluorescent dye with alkenyl indole as parent nucleus and preparation and application thereof 温州医科大学附属第一医院 2023-08-01 — — CN disclosed
WO-2015089218-A1 MONOCYCLIC PYRIMIDINE/PYRIDINE COMPOUNDS AS INHIBITORS OF P97 COMPLEX WUSTROW DAVID (US) 2015-06-18 — — WO disclosed
EP-2563774-A1 PYRIMIDINYL INDOLE COMPOUNDS Hutchison Medipharma Limited (CN) 2013-03-06 — — EP disclosed
WO-2011134140-A1 PYRIMIDINYL INDOLE COMPOUNDS HUTCHISON MEDIPHARMA LIMITED (CN) 2011-11-03 — — WO disclosed
CN-101257948-A Pyrimidine-fused diazepine derivatives and indole-fused pteridines ATTENUON LLC (US) 2008-09-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10940468-B2 Nickel catalyst, process for preparation and use thereof NISCH, NIT2, C9 RPS6KA5 3540/4885CDC7 1430/4885CDK2 2978/4885
US-20260015332-A1 SYNTHESIS METHOD AND APPLICATION OF BENZOTHIASELENAZOLE-1-OXIDE COMPOUND AND DERIVATIVE THEREOF SARS1, EGFR, ERBB2 RPS6KA5 1460/4885CDC7 2360/4885CDK2 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.