SCHEMBL25901608

SCHEMBL25901608

CCN(C(=O)OCOC(=O)[C@@H](N)C(C)C)C(C)Cc1ccc2c(c1)OCO2

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.47
SLC6A4 P31645 3/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A3 Q01959 2/20 0.47
CYP3A4 P08684 3/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ATM Q13315 1/20 0.42
SLC5A1 P13866 1/20 0.41
SLC5A2 P31639 1/20 0.41
CYP2D6 P10635 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25907252 1.00 TAAR1 (0.47) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901887 1.00 TAAR1 (0.47) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901893 0.93 TAAR1 (0.46) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901890 0.92 TAAR1 (0.46) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901886 0.92 TAAR1 (0.49) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901495 0.91 CYP3A4 (0.47) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901892 0.89 TAAR1 (0.46) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901888 0.88 TAAR1 (0.46) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL24884041 0.88 TAAR1 (0.49) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL25901787 0.88 TAAR1 (0.46) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137446-A1 PRODRUGS OF 3,4-METHYLENEDIOXY- N-ETHYL-AMPHETAMINE (MDEA) AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed