Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596296 | 0.87 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7700075 | 0.87 | PDE10A (0.81) | PDE10A | |
| SCHEMBL12029539 | 0.87 | PDE10A (0.77) | PDE10A | |
| SCHEMBL2593573 | 0.85 | PDE10A (0.85) | PDE10A | |
| SCHEMBL2596313 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596134 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596334 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596130 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2593886 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2595788 | 0.83 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569300-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | Amgen Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |