Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 11/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 3/20 | 0.34 |
| ▸ | YES1 | P07947 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | LYN | P07948 | 2/20 | 0.34 |
| ▸ | FGR | P09769 | 2/20 | 0.34 |
| ▸ | FRK | P42685 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25677247 | 0.90 | MTOR (0.47) | MTORRPTORMLST8PIK3C2BHDAC1 | |
| SCHEMBL25064546 | 0.90 | MTOR (0.47) | MTORRPTORMLST8PIK3C2BHDAC1 | |
| SCHEMBL23251564 | 0.90 | MTOR (0.47) | MTORRPTORMLST8PIK3C2BHDAC1 | |
| SCHEMBL23251755 | 0.90 | MTOR (0.47) | MTORRPTORMLST8PIK3C2BHDAC1 | |
| SCHEMBL25903766 | 0.86 | MTOR (0.41) | MTORRPTORMLST8PIK3C2BHDAC1 | |
| SCHEMBL25064448 | 0.85 | MTOR (0.53) | MTORRPTORMLST8HDAC1HDAC3 | |
| SCHEMBL23251576 | 0.85 | MTOR (0.53) | MTORRPTORMLST8HDAC1HDAC3 | |
| SCHEMBL23251631 | 0.85 | MTOR (0.53) | MTORRPTORMLST8HDAC1HDAC3 | |
| SCHEMBL23251761 | 0.85 | MTOR (0.53) | MTORRPTORMLST8HDAC1HDAC3 | |
| SCHEMBL24519378 | 0.85 | MTOR (0.54) | MTORRPTORMLST8HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | KRAS, HRAS, MTOR | MTOR 3/4885RPTOR 8/4885MLST8 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.