Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 13/20 | 0.42 |
| ▸ | RARG | P13631 | 9/20 | 0.42 |
| ▸ | RXRB | P28702 | 8/20 | 0.42 |
| ▸ | RXRG | P48443 | 7/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (+)-Abscisic Acid SCHEMBL2590419 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL11994582 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL2590414 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL15042784 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL2591175 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL2591173 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL3107122 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL33613 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL14137764 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG | |
| (+)-Abscisic Acid SCHEMBL28818082 | 1.00 | TSHR (1.00) | TSHRHIF1ALANCL2RXRARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150241448-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150241448-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150241448-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| US-9101573-B2 | Lanthionine synthetase component C-like proteins as molecular targets for preventing and treating diseases and disorders | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-9101573-B2 | Lanthionine synthetase component C-like proteins as molecular targets for preventing and treating diseases and disorders | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-9101573-B2 | Lanthionine synthetase component C-like proteins as molecular targets for preventing and treating diseases and disorders | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | LANCL2, ACSL1, LANCL1 | TSHR 523/4885HIF1A 1154/4885LANCL2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.