Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591870 | 0.77 | ACACB (0.40) | ACACBMMP2MMP12FFAR1USP5 | |
| SCHEMBL22964321 | 0.77 | GRM5 (0.37) | ACACBMMP2MMP12GRM5ALOX5 | |
| SCHEMBL21214839 | 0.73 | GRM5 (0.36) | ACACBMMP2MMP12GRM5ALOX5 | |
| SCHEMBL18591869 | 0.73 | ACACB (0.37) | ACACBMMP2MMP12 | |
| SCHEMBL20325131 | 0.71 | GRM5 (0.35) | ACACBGRM5ALOX5 | |
| SCHEMBL18611814 | 0.71 | ACACB (0.41) | ACACB | |
| SCHEMBL22047351 | 0.71 | ACACB (0.41) | ACACB | |
| SCHEMBL18611812 | 0.71 | ACACB (0.41) | ACACB | |
| SCHEMBL19036905 | 0.71 | GRM5 (0.43) | ACACBFFAR1GRM5 | |
| SCHEMBL29339386 | 0.70 | ACACB (0.40) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | AAAS, PROC, AADAC | ACACB 593/4885MMP2 608/4885MMP12 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.