Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469146 | 0.89 | TDP1 (0.47) | TDP1DHODHADORA2ABCL2L1BAD | |
| SCHEMBL2465142 | 0.89 | TDP1 (0.54) | TDP1DHODHADORA2AKMOADORA1 | |
| SCHEMBL2467801 | 0.87 | TDP1 (0.56) | TDP1DHODHADORA2AKMOADORA1 | |
| SCHEMBL20727095 | 0.86 | TDP1 (0.51) | TDP1DHODHADORA2AKMOADORA1 | |
| SCHEMBL16075456 | 0.86 | TDP1 (0.51) | TDP1DHODHADORA2AKMOADORA1 | |
| SCHEMBL16075485 | 0.86 | TDP1 (0.51) | TDP1DHODHKMOMAPTKDM4E | |
| SCHEMBL2468818 | 0.85 | PLAU (0.49) | TDP1DHODHKDM4EALDH1A1HPGD | |
| SCHEMBL16075393 | 0.82 | TDP1 (0.47) | TDP1ADORA2AKMOADORA1 | |
| SCHEMBL16075471 | 0.82 | TDP1 (0.47) | TDP1DHODHKMOMAPTKDM4E | |
| SCHEMBL2469142 | 0.82 | PDCD1 (0.48) | TDP1DHODHADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-B1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-07-12 | — | — | EP | disclosed |