Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 3/20 | 0.31 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907891 | 1.00 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907399 | 1.00 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25909202 | 1.00 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25908820 | 1.00 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907888 | 0.90 | ATR (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907394 | 0.90 | ATR (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907393 | 0.90 | ATR (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907890 | 0.90 | ATR (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25908783 | 0.90 | ATR (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25159999 | 0.82 | ATR (0.46) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |