Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 4/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907412 | 0.93 | CHEK1 (0.35) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907422 | 0.92 | CHEK1 (0.36) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907411 | 0.91 | CHEK1 (0.34) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907408 | 0.91 | CHEK1 (0.34) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907420 | 0.91 | CHEK1 (0.36) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907417 | 0.91 | ATR (0.35) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907402 | 0.90 | CHEK1 (0.35) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907415 | 0.89 | CHEK1 (0.33) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907414 | 0.89 | PIK3CD (0.34) | CHEK1CCNA2CDK2CCNA1ATR | |
| SCHEMBL25907579 | 0.89 | CHEK1 (0.35) | CHEK1CCNA2CDK2CCNA1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |