Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24962176 | 0.84 | RAD52 (0.42) | DPP4MAP3K12PIK3CA | |
| SCHEMBL25908456 | 0.84 | PDE10A (0.51) | DPP4MAP3K12PIK3CA | |
| SCHEMBL24962187 | 0.78 | ATR (0.38) | DPP4MAP3K12MAP3K7 | |
| SCHEMBL24962177 | 0.77 | RAD52 (0.40) | DPP4 | |
| SCHEMBL24962396 | 0.77 | DPP4 (0.33) | DPP4MAP3K12PIK3CAPIK3R1MAP3K7 | |
| SCHEMBL27233155 | 0.77 | DPP4 (0.33) | DPP4MAP3K12PIK3CAPIK3R1MAP3K7 | |
| SCHEMBL30893787 | 0.75 | SMPD3 (0.38) | MAP3K12PIK3CAJAK2TYK2 | |
| SCHEMBL24962095 | 0.75 | SMPD3 (0.38) | MAP3K12PIK3CAJAK2TYK2 | |
| SCHEMBL25908367 | 0.74 | PIK3CA (0.36) | DPP4MAP3K12PIK3CAPIK3R1 | |
| SCHEMBL25908450 | 0.73 | MAP3K7 (0.43) | DPP4MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138343-A1 | NEW TYPE PYRAZOLOPYRIMIDINE COMPOUND AND COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏亚尧生物科技有限公司 | 2023-07-27 | — | — | WO | disclosed |