Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.76 |
| ▸ | CDK2 | P24941 | 20/20 | 0.76 |
| ▸ | CCND1 | P24385 | 19/20 | 0.76 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.76 |
| ▸ | CDK4 | P11802 | 4/20 | 0.76 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.76 |
| ▸ | CDK9 | P50750 | 3/20 | 0.76 |
| ▸ | CCND3 | P30281 | 3/20 | 0.62 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.60 |
| ▸ | RB1 | P06400 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908823 | 0.89 | CCND1 (0.77) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25909065 | 0.88 | CCND1 (0.69) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25909491 | 0.88 | CCND1 (0.69) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL30550413 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL30550124 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25316105 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL26472010 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19863639 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19863641 | 0.86 | CCNE1 (1.00) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25908745 | 0.86 | CCNE1 (0.75) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242526-A1 | Deuterated Pyridopyrimidinones And Their Use As Highly Selective Cyclin-Dependent Kinase 2 Inhibitors | ZENTAUR THERAPEUTICS INTERNATIONAL LIMITED (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242526-A1 | Deuterated Pyridopyrimidinones And Their Use As Highly Selective Cyclin-Dependent Kinase 2 Inhibitors | CDK2, CDK4, CCNI | CCNE1 47/4885CDK2 1/4885CCND1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.