SCHEMBL25909329

SCHEMBL25909329

CCCCCCCCCCCCCCCCOC(C)C[C@H](O)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.42
MCHR1 Q99705 1/20 0.37
PLA2G4B P0C869 1/20 0.37
STAT3 P40763 1/20 0.36
ALDH1A1 P00352 3/20 0.35
PSMD10 O75832 1/20 0.35
CYP3A4 P08684 1/20 0.34
LMNA P02545 2/20 0.33
CNR2 P34972 1/20 0.33
S1PR3 Q99500 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALB P02768 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MMP3 P08254 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723718 0.88 PLA2G2C (0.44) PLA2G2CMCHR1STAT3ALDH1A1CYP3A4
SCHEMBL9512608 0.88 PLA2G2C (0.44) PLA2G2CMCHR1STAT3ALDH1A1CYP3A4
SCHEMBL9488453 0.88 PLA2G2C (0.44) PLA2G2CMCHR1STAT3ALDH1A1CYP3A4
SCHEMBL9723827 0.86 PLA2G2C (0.42) PLA2G2CMCHR1STAT3ALDH1A1CYP3A4
SCHEMBL6818282 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4
SCHEMBL6814001 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4
SCHEMBL25956397 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4
SCHEMBL9575934 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4
SCHEMBL9575937 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4
SCHEMBL25967510 0.83 PLA2G2C (0.53) PLA2G2CMCHR1PLA2G4BALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. 2023-07-27 US disclosed
US-11638715-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2023-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638715-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP PLA2G2C 3210/4885MCHR1 4167/4885PLA2G4B 2366/4885
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS SLC29A2, SLC29A1, PNP PLA2G2C 3210/4885MCHR1 4167/4885PLA2G4B 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.