Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | MYLK | Q15746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9933289 | 0.98 | KDM4E (0.46) | KDM4ECYP3A4NFKB1CYP2D6MYLK | |
| SCHEMBL20507730 | 0.82 | KDM4E (0.52) | KDM4ECYP3A4NFKB1CYP2D6MYLK | |
| Hydrochloric Acid SCHEMBL13386352 | 0.81 | KDM4E (0.50) | KDM4ECYP3A4NFKB1CYP2D6MYLK | |
| SCHEMBL1161139 | 0.73 | KDM4E (0.48) | KDM4ECYP3A4NFKB1KMT2ALMNA | |
| SCHEMBL9936711 | 0.73 | KDM4E (0.48) | KDM4ECYP3A4NFKB1KMT2ALMNA | |
| SCHEMBL30440853 | 0.71 | KDM4E (0.58) | KDM4ECYP3A4NFKB1CYP2D6MYLK | |
| Hydrochloric Acid SCHEMBL189808 | 0.71 | KDM4E (0.46) | KDM4ECYP3A4NFKB1LMNATSHR | |
| SCHEMBL25176113 | 0.70 | KDM4E (0.50) | KDM4ECYP3A4NFKB1LMNATSHR | |
| SCHEMBL92545 | 0.70 | KDM4E (0.56) | KDM4ECYP3A4NFKB1CYP2D6MYLK | |
| Hydrochloric Acid SCHEMBL9934025 | 0.70 | KDM4E (0.56) | KDM4ECYP3A4NFKB1CYP2D6MYLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585073-A1 | ANTIVIRAL COMPOUNDS | Prostetta Antiviral Inc. (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011137447-A1 | ANTIVIRAL COMPOUNDS | PROSTETTA ANTIVIRAL INC. (US) | 2011-11-03 | — | — | WO | disclosed |