Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 11/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913246 | 1.00 | BRAF (0.41) | BRAFMAPK14PDGFRBCSF1RPDGFRA | |
| SCHEMBL25910701 | 0.93 | SCN9A (0.38) | BRAFPDGFRBCSF1RKDRSCN9A | |
| SCHEMBL25910828 | 0.91 | BRAF (0.45) | BRAFMAPK14PDGFRBCSF1RPDGFRA | |
| SCHEMBL25910285 | 0.89 | PDGFRB (0.45) | BRAFMAPK14PDGFRBCSF1RPDGFRA | |
| SCHEMBL25910414 | 0.88 | PDGFRB (0.45) | BRAFMAPK14PDGFRBCSF1RPDGFRA | |
| SCHEMBL25910552 | 0.86 | BRAF (0.42) | BRAFPDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910699 | 0.83 | CSF1R (0.51) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25910556 | 0.82 | PDGFRB (0.49) | BRAFMAPK14PDGFRBCSF1RPDGFRA | |
| SCHEMBL25910691 | 0.82 | CSF1R (0.38) | BRAFPDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910809 | 0.82 | BRAF (0.45) | BRAFMAPK14PDGFRBCSF1RPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |